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Search Results for " cbp 1 "

Targets Recommended: Epigenetic Reader Domain

29

抑制剂 & 化合物

1

天然产物

1738

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T7264	CBP/EP300-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	CBP/EP300-IN-1是一种 CBP/EP300 溴结构域抑制剂。
T10717	Inobrodib CBP-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	Inobrodib (CBP-IN-1) 是一种口服活性的强选择性p300/CBP 抑制剂，与 p300 和 CBP 结合，Kd 值为 1.3 和 1.7 nM。它抑制前列腺癌细胞系的细胞增殖并降低雄激素受体和 C-MYC 调节的基因表达。
T3973	PF-CBP1	Epigenetic Reader Domain	Chromatin/Epigenetic
	PF-CBP1 是一种高选择性的 CREB 结合蛋白 (CREBBP) 溴结构域抑制剂。它抑制 CREBBP (IC50: 125 nM) 和 p300 溴结构域 (IC50: 363 nM)。
T3217	PF-CBP1 hydrochloride PF-CBP1 HCl	Epigenetic Reader Domain; Histone Acetyltransferase	Chromatin/Epigenetic
	PF-CBP1 hydrochloride (PF-CBP1 HCl) 是 CREB 结合蛋白溴结构域的一种高选择性抑制剂，抑制 CREBBP 和 EP300溴结构域的 IC50分别为 125 和 363 nM。它降低 LPS 诱导的巨噬细胞中炎症因子的表达，也可下调皮质神经元 RGS4 的表达，可用于癫痫和帕金森病等神经疾病的研究。
T40143	PROTAC CBP/P300 Degrader-1 PROTAC CBP/P300 Degrader-1	PROTACs	PROTAC
	PROTAC CBP/P300 Degrader-1 is an effective compound that degrades CBP/P300 in a potent manner. It significantly reduces cell viability in various cancer cell lines.
T12537	β-catenin/CBP-IN-1	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin
T9370	dCBP-1	Epigenetic Reader Domain; Ligand for E3 Ligase; PROTACs	Chromatin/Epigenetic; PROTAC
	dCBP-1 是基于Cereblon 配体的p300/CBP 的选择性双功能降解剂。dCBP-1可以有效的杀死多发性骨髓瘤细胞，并降低驱动 MYC 表达的致癌增强子活性。
T3635	IQ 1 IQ1,IQ-1	Wnt/beta-catenin	Cytoskeletal Signaling; Stem Cells
	IQ 1 有多种作用，如保持小鼠ESCs 的多功能性、降低Wnt 刺激的磷酸化、阻止PP2A/Nkd 的相互作用等等。
T79168	CBP-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	CBP-IN-1（化合物12）是一种高效CBP抑制剂，其IC50为1.5 nM。此外，该化合物对CBP BRET和BRD4(1)的抑制作用，其IC50分别达到690 nM和3100 nM。
T9373	DCH36_06 (5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione	Apoptosis; Epigenetic Reader Domain; Histone Acetyltransferase	Apoptosis; Chromatin/Epigenetic
	DCH36_06 ((5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione) 是一种选择性p300/CBP 抑制剂，介导 p300/CBP 抑制导致白血病细胞中 H3K18 的低乙酰化，有抗肿瘤活性，对p300和CBP 的IC50分别为 0.6 μM 和 3.2 μM。
T6811	CPI-637 CPI 637	Epigenetic Reader Domain; Histone Acetyltransferase	Chromatin/Epigenetic
	CPI-637 是一种选择性和细胞活性的苯二氮卓 CBP/EP300 溴结构域抑制剂，其对 CBP、EP300和 BRD4 BD-1的 IC50值分别为 0.03、0.051 和 11.0 μM，对 CBP 的 EC50值为 0.3 μM。
T15405	GNE-781	Epigenetic Reader Domain	Chromatin/Epigenetic
	GNE-781 是一种具有口服活性的选择性 CBP 抑制剂，在 TR-FRET 实验中 IC50为 0.94 nM。它还抑制BRET 和BRD4 (1)，IC50分别为 6.2 和 5100 nM，有抗肿瘤活性。
T4247	I-CBP112 hydrochloride	Epigenetic Reader Domain	Chromatin/Epigenetic
	I-CBP112 hydrochloride 是含溴结构域转录因子的选择性抑制剂，靶向 CBP/p300 溴结构域。在体内外，它以剂量依赖性方式显着降低 MLL-AF9(+) 急性髓细胞白血病细胞的白血病起始潜力，还增加 BET 溴结构域抑制剂 JQ1 以及阿霉素的细胞毒活性。
T39826	CBP/p300-IN-8 CBP/p300-IN-8
	CBP/p300-IN-8 is a potent inhibitor of the CBP/P300 family of bromodomains . CBP/p300-IN-8 inhibits CBP ( IC 50 =0.01-0.1 μΜ) and BRD4 ( IC 50 =1-1000 μΜ) activity.
T15399	GNE-207	Epigenetic Reader Domain	Chromatin/Epigenetic
	GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM). It has a selective index of >2500-fold against BRD4 (1). GNE-207 displays excellent CBP potency (EC50: 18 nM for MYC expression in MV-4-11 cells).
T62700	CBP/p300-IN-16
	CBP/p300-IN-16 (compound 1) 是一种 EP300/CBP HAT 的有效抑制剂，作用于 HAT EP300 (IC50: 0.61 μM) 和 LK2 H3K27 (IC50: 2.24 μM)。
T40144	CBP/p300 ligand 2
	CBP/p300 ligand 2 is a selective ligand that binds to the target protein for PROTAC of dCBP-1, a potent and selective heterobifunctional degrader of p300/CBP.
T79395	CBP/p300-IN-21	Epigenetic Reader Domain	Chromatin/Epigenetic
	CBP/p300-IN-21 (Compound 5d) 作为一种选择性CBP/p300抑制剂，展现出对p300和CBP具有差异性的IC50值，分别为0.07 μM和1.755 μM。该化合物能有效降低H3K18Ac的水平，并抑制小鼠4T1肿瘤的生长。
T61314	DC-CPin7
	DC-CPin7, a powerful inhibitor of the bromodomain of CREB-binding protein (CBP), exhibits an IC50 value of 2.5 μM [1].
T40036	Thalidomide-NH-PEG4-COOH Thalidomide-NH-PEG4-COOH
	Thalidomide-NH-PEG4-COOH is a conjugate comprising an E3 ligase ligand-linker, utilized in the synthesis of dCBP-1. dCBP-1 itself functions as a powerful and selective heterobifunctional degrader targeting p300/CBP.
T15397	GNE-049	Epigenetic Reader Domain	Chromatin/Epigenetic
	GNE-049 is a highly potent and selective inhibitor of CBP (IC50: 1.1 nM in TR-FRET assay). GNE-049 also inhibits BRET and BRD4(1) (IC50s: 12 nM and 4200 nM, respectively).
T60479	NSC 698600
	NSC 698600 是一种有效的 PCAF（p300/CBP 相关因子）抑制剂，IC50值为 6.51 μM，显示出良好的癌细胞增殖抑制活性。
T79230	JET-209	PROTACs	PROTAC
	JET-209为高效PROTAC CBP/p300降解剂，DC50分别为CBP和p300的0.05 nM与0.2 nM。该化合物融合了Lenalidomide (cereblon配体)、连接子以及GNE-207 (溴结构域抑制剂)。JET-209主要应用于癌症研究领域。
T61719	DC-CPin711
	DC-CPin711, a potent and selective inhibitor of the bromodomain of CREB-binding protein (CBP) with an IC50 of 0.0626 μM, effectively halts the cell cycle at the G1 phase and promotes apoptosis [1].
T60888	NiCur
	NiCur 可阻断CBP HAT 活性并在基因毒性应激时下调 p53 的激活。NiCur 是CBP 组蛋白乙酰转移酶 (HAT)的有效选择性抑制剂，IC50值为 0.35 μΜ。 NiCur 可用于机制研究，不影响目标蛋白的表达。
T78715	MS78
	MS78为一种乙酰化靶向嵌合体(AceTAC)，其功能是招募组蛋白乙酰转移酶p300/CBP以乙酰化p53肿瘤抑制蛋白的p53Y220C突变体。通过该作用，MS78能够上调TRAIL凋亡基因，同时下调DNA损伤反应信号通路。此化合物结构包含CBP/p300结合物、p53Y220C结合物及linker。
T74823	Bromodomain IN-2
	BD-IN-1 是一种泛溴结构域 (bromodomain (BD)) 抑制剂，对BRD4(1), CBP, BRPF1B,BRD7,BRD9, BRDT(1),CECR2的KD 值分别为 250、420、130、430、67、240、970 nM。BD-IN-1 具有抗增殖活性。
T81314	Rademikibart CBP-201
	Rademikibart (CBP-201) 是一款针对IL-4Rα的人源化单克隆抗体，其与人IL-4Rα的结合亲和力KD值为20.7 pM。该抗体不与其他物种的IL-4Rα发生交互作用。Rademikibart 能够抑制PBMC中IL-4及IL-13介导的STAT6信号通路、TF-1细胞的增殖以及TARC的产生，显示出其在中到重度Th2型炎症性疾病研究中的应用潜力。
T69014	Sekikaic Acid
	Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µM. Sekikaic acid is active against the rg recombinant strain of respiratory syncytial virus (RSV; IC50 = 5.69 µg/ml). It inhibits the protein-protein interaction between mixed lineage leukemia 1 (MLL1) and the GACKIX domain of CREB-binding protein (CBP; IC50 = 34 µM).

化合物

CBP/EP300-IN-1

Cat.No: T7264

Target: Epigenetic Reader Domain

Cat.No: T10717

Synonym: CBP-IN-1

Target: Epigenetic Reader Domain

Cat.No: T3973

Target: Epigenetic Reader Domain

PF-CBP1 hydrochloride

Cat.No: T3217

Synonym: PF-CBP1 HCl

Target: Epigenetic Reader Domain, Histone Acetyltransferase

PROTAC CBP/P300 Degrader-1

Cat.No: T40143

Synonym: PROTAC CBP/P300 Degrader-1

Target: PROTACs

β-catenin/CBP-IN-1

Cat.No: T12537

Target: Wnt/beta-catenin

Cat.No: T9370

Target: Epigenetic Reader Domain, Ligand for E3 Ligase, PROTACs

Cat.No: T3635

Synonym: IQ1,IQ-1

Target: Wnt/beta-catenin

Cat.No: T79168

Target: Epigenetic Reader Domain

Cat.No: T9373

Synonym: (5E)-1-(3-chloro-4-methylphenyl)-5-[(2E)-3-(furan-2-yl)prop-2-en-1-ylidene]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione

Target: Apoptosis, Epigenetic Reader Domain, Histone Acetyltransferase

Cat.No: T6811

Synonym: CPI 637

Target: Epigenetic Reader Domain, Histone Acetyltransferase

Cat.No: T15405

Target: Epigenetic Reader Domain

I-CBP112 hydrochloride

Cat.No: T4247

Target: Epigenetic Reader Domain

CBP/p300-IN-8

Cat.No: T39826

Synonym: CBP/p300-IN-8

Cat.No: T15399

Target: Epigenetic Reader Domain

CBP/p300-IN-16

Cat.No: T62700

CBP/p300 ligand 2

Cat.No: T40144

CBP/p300-IN-21

Cat.No: T79395

Target: Epigenetic Reader Domain

Cat.No: T61314

Thalidomide-NH-PEG4-COOH

Cat.No: T40036

Synonym: Thalidomide-NH-PEG4-COOH

Cat.No: T15397

Target: Epigenetic Reader Domain

Cat.No: T60479

Cat.No: T79230

Target: PROTACs

Cat.No: T61719

Cat.No: T60888

Cat.No: T78715

Bromodomain IN-2

Cat.No: T74823

Cat.No: T81314

Synonym: CBP-201

Cat.No: T69014

Cat. No.	Product Name	Target	Signaling Pathways
TN1567	Delphinidin chloride	Estrogen Receptor/ERR; VEGFR	Angiogenesis; Endocrinology/Hormones; Tyrosine Kinase/Adaptors
	Delphinidin chloride 是一种花青素，是一种可从浆果和红酒中分离得到的天然植物色素，是某些花青素的前体。Delphinidin chloride 诱导血管内皮释放一氧化氮，引起血管松弛。在1 ~ 40 μM 剂量下，对上皮生长因子受体的信号传导和雌激素受体α的表达有抑制作用，与细胞凋亡和自噬有关。Delphinidin chloride 能调节 JAK/STAT3 和 MAPKinase 信号传导。Delphinidin 还能抑制 p300/CBP 的组蛋白乙酰转移酶活性(IC50 在约为30 μM)

天然产物

Delphinidin chloride

Cat.No: TN1567

Target: Estrogen Receptor/ERR, VEGFR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02611	Galectin-8 Protein, Human, Recombinant lectin, galactoside-binding, soluble, 8,PCTA-1,Po66...	Human	E. coli
	Galectin-8 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 35.5 kDa and the accession number is AAF19370.1.
TMPY-02326	Galectin-8 Protein, Human, Recombinant (GST) PCTA1,Po66-CBP,PCTA-1,lectin, gal...	Human	E. coli
	Galectin-8 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 62.7 kDa and the accession number is AAF19370.1.
TMPJ-00654	LGALS8 Protein, Human, Recombinant Prostate Carcinoma Tumor Antigen 1,Po66-CBP	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. Although they are localized primarily in the cytoplasm and lack a classical signal peptide, galectins can also be...
TMPJ-00995	Serpin H1 Protein, Human, Recombinant (His) Arsenic-Transactivated Protein 3,SERPINH2,Rheumatoid Arthrit...	Human	HEK293 Cells
	Serpin H1 is a serine proteinase inhibitors Which belongs to the serpin family. Serpin H1 is induced by heat shock. Serpin H1 localizes to the endoplasmic reticulum lumen and binds specifically to collagen. Thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis. Serpin H1 may be a marker for cancer and nucleotide polymorphisms in this gene may be associated with preterm ...
TMPH-01512	HIF1AN Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and severa...
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) AMPK, AMPK(α1, β1, γ1)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone...	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu...	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-05039	LTBR Protein, Human, Recombinant (hFc) TNFR-RP,lymphotoxin β receptor (TNFR superfamily, member 3),...	Human	HEK293 Cells
	LTBR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is P36941-1.
TMPY-04753	IRE1 Protein, Human, Recombinant (aa 465-977) hIRE1p,endoplasmic reticulum to nucleus signaling <...	Human	Baculovirus Insect Cells
	IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells. The predicted molecular weight is 58.3 kDa and the accession number is O75460-1.
TMPY-02112	FGFR4 Protein, Human, Recombinant (His) TKF,JTK2,CD334,fibroblast growth factor receptor 4	Human	HEK293 Cells
	FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPY-00740	SDF-1 Protein, Human, Recombinant (hFc) PBSF,IRH,chemokine (C-X-C motif) ligand 12,SDF1...	Human	HEK293 Cells
	SDF-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is P48061-1.
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His) VEGFR2,kinase insert domain receptor,VEGFR,FLK1,Flk...	Human	HEK293 Cells
	VEGFR2/KDR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.6 kDa and the accession number is P35968-1.
TMPY-02904	TLR4 Protein, Human, Recombinant (His) TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284	Human	Baculovirus Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed...
TMPY-00972	FGFR2 Protein, Human, Recombinant (His & hFc) K-SAM,TK14,BBDS,fibroblast growth factor receptor 2...	Human	HEK293 Cells
	FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1.
TMPY-02591	SDF-1 Protein, Human, Recombinant SDF1,chemokine (C-X-C motif) ligand 12,TPA...	Human	E. coli
	SDF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.6 kDa and the accession number is P48061-1.
TMPY-01053	Prolactin Receptor Protein, Human, Recombinant (His) hPRLrI,PRLR,MFAB,HPRL,prolactin receptor	Human	HEK293 Cells
	Prolactin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is P16471-1.
TMPY-06077	LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) LIR-6,leukocyte immunoglobulin like receptor A1,LIR...	Human	HEK293 Cells
	LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 75.3 kDa and the accession number is O75019-1.
TMPY-00277	IL-18 Protein, Human, Recombinant IGIF,IL-18,IL1F4,IL-1g,Interleuki...	Human	E. coli
	IL-18 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is Q14116-1.
TMPY-00686	Complement C2 Protein, Human, Recombinant (His) CO2,complement component 2,ARMD14	Human	HEK293 Cells
	Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1.
TMPY-00381	PSMA Protein, Human, Recombinant (His) FGCP,GCP2,PSMA,GCPII,NAALAdase,folate hydrolase (prostate-sp...	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
TMPY-04684	HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His) HERVWENV,MLN 19,HERV7Q,HERVW,CD340,NGL,erb-b2 recep...	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is P04626-1.
TMPY-01458	GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His) GDNF family receptor α3,GDNFR3,GDNF family receptor alpha 3,...	Human	HEK293 Cells
	GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.8 kDa and the accession number is O60609-1.
TMPY-02836	MFGE8 Protein, Human, Recombinant (His) SPAG10,HMFG,milk fat globule-EGF factor 8 protein,h...	Human	Baculovirus Insect Cells
	MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1.
TMPY-01305	OSMR Protein, Human, Recombinant (His) OSMRB,PLCA1,oncostatin M receptor,IL-31RB	Human	HEK293 Cells
	OSMR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.6 kDa and the accession number is Q99650-1.
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His) FCGRIII,Fc gamma RIIIa,FCR-10,FCRIII,FCRIIIA,FCGR3...	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also known as CD16a, encodes a transmembrane protein expressed on activated monocytes/macrophages, natural killer (NK) cells, and a subset of T cells. CD16a / FCGR3A is a receptor expressed on NK cells that facilitates antibody dependent cellular cytotoxicity (ADCC) by binding to the...
TMPY-01650	CD131 Protein, Human, Recombinant (His) CDw131,IL5RB,colony stimulating factor 2 r...	Human	HEK293 Cells
	CD131 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is P32927-1.
TMPY-01829	CD83 Protein, Human, Recombinant (His) BL11,HB15,CD83 molecule	Human	HEK293 Cells
	CD83 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is Q01151-1.
TMPY-02205	Beta-Catenin Protein, Human, Recombinant (His & GST) catenin beta 1,armadillo,CTNNB,MRD19,caten...	Human	Baculovirus Insect Cells
	Beta-Catenin Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 113 kDa and the accession number is P35222-1.
TMPY-00545	Dermcidin Protein, Human, Recombinant (hFc) AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP	Human	HEK293 Cells
	Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ...
TMPY-06982	IGF1/IGF-I Protein, Human, Recombinant insulin-like growth factor 1,somatomedin C,胰岛素样生长因子...	Human	E. coli
	IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1.
TMPY-01084	TrkA Protein, Human, Recombinant (His) TRK1,TRK,TRKA,neurotrophic tyrosine kinase, recepto...	Human	HEK293 Cells
	TrkA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is P04629-1.
TMPY-01963	IL-21 Protein, Human, Recombinant CVID11,IL-21,白介素,白细胞介素,Za1	Human	E. coli
	IL-21 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.6 kDa and the accession number is Q9HBE4-1.
TMPY-06247	TGF beta 3 Protein, Human, Recombinant (hFc) TGF-beta 3,ARVD,TGF β3,TGF-β3,TGF-beta3,transforming growth ...	Human	HEK293 Cells
	TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is P10600-1.
TMPY-01703	TREM-2 Protein, Mouse, Recombinant (His) Trem2b,TREM-2,Trem2c,triggering receptor expressed on myeloi...	Mouse	HEK293 Cells
	TREM-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is Q99NH8-1.
TMPY-01461	EMAP-II/AIMP1 Protein, Human, Recombinant (His) SCYE1,p43,EMAPII,aminoacyl tRNA synthetase complex-...	Human	E. coli
	EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1.
TMPY-02170	SCF Protein, Human, Recombinant (aa 1-189, His) DCUA,Kitl,FPHH,SCF,KL-1,SF,FPH2,MGF,SHEP7,C-kit lig...	Human	Baculovirus Insect Cells
	SCF Protein, Human, Recombinant (aa 1-189, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is P21583-1.
TMPY-01885	Human RSV (B1) glycoprotein G/RSV-G Protein (His) G Protein, RSV	RSV	HEK293 Cells
	Human RSV (B1) glycoprotein G/RSV-G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27 kDa and the accession number is O36633-1.
TMPY-01283	Glypican 3/GPC3 Protein, Human, Recombinant (His) SGBS1,DGSX,SGBS,MXR7,OCI-5,Glypican 3,SGB,SDYS,GTR2...	Human	HEK293 Cells
	Glypican 3/GPC3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62 kDa and the accession number is P51654-1.
TMPY-02700	BCL2 Protein, Human, Recombinant (His) Bcl-2,PPP1R50,B-cell CLL/lymphoma 2	Human	E. coli
	BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins...
TMPY-05840	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) interleukin 1 receptor accessory protein	Cynomolgus	HEK293 Cells
	IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1.
TMPY-01032	CD299 Protein, Human, Recombinant (hFc) LSIGN,CLEC4M,C-type lectin domain family 4 member M,MGC47866...	Human	HEK293 Cells
	CD299 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is Q9H2X3-1.
TMPY-01813	ACRV1 Protein, Human, Recombinant (His) SP-10,SPACA2,D11S4365,acrosomal v...	Human	HEK293 Cells
	Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest tr...
TMPY-02953	TEM8/ANTXR1 Protein, Human, Recombinant (hFc) ATR,TEM8,anthrax toxin receptor 1,GAPO	Human	HEK293 Cells
	ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro...
TMPY-02603	STAT6 Protein, Human, Recombinant (His) STAT6C,IL-4-STAT,STAT6B,signal transducer and activator of t...	Human	Baculovirus Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators...
TMPY-04096	ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) Ly84,St2-rs1,T1,ST2L,T1/ST2,Fit-<...	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is P14719-1.
TMPY-05781	LILRA6 Protein, Human, Recombinant (His) LILRB6,ILT-8,ILT5,LILRB3,ILT8,CD85b	Human	HEK293 Cells
	LILRA6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.78 kDa and the accession number is Q6PI73-1.
TMPY-01003	TCN2 Protein, Human, Recombinant (His) II,TC-2,D22S750,TC,TCII,TC2,transcobalamin II,D22S676	Human	HEK293 Cells
	TCN2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.7 kDa and the accession number is P20062-1.
TMPY-00925	SOST Protein, Human, Recombinant (His) VBCH,sclerostin,DAND6,CDD,SOST1	Human	HEK293 Cells
	SOST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.5 kDa and the accession number is Q9BQB4-1.
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重组蛋白

Galectin-8 Protein, Human, Recombinant

Cat.No: TMPY-02611

Species: Human

Expression System: E. coli

Galectin-8 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02326

Species: Human

Expression System: E. coli

LGALS8 Protein, Human, Recombinant

Cat.No: TMPJ-00654

Species: Human

Expression System: E. coli

Serpin H1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00995

Species: Human

Expression System: HEK293 Cells

HIF1AN Protein, Human, Recombinant (His)

Cat.No: TMPH-01512

Species: Human

Expression System: P. pastoris (Yeast)

AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04451

Species: Human

Expression System: Baculovirus Insect Cells

Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03878

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant

Cat.No: TMPY-02501

Species: Human

Expression System: HEK293 Cells

CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)

Cat.No: TMPY-03745

Species: Human

Expression System: HEK293 Cells

LTBR Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05039

Species: Human

Expression System: HEK293 Cells

IRE1 Protein, Human, Recombinant (aa 465-977)

Cat.No: TMPY-04753

Species: Human

Expression System: Baculovirus Insect Cells

FGFR4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02112

Species: Human

Expression System: HEK293 Cells

SDF-1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00740

Species: Human

Expression System: HEK293 Cells

VEGFR2/KDR Protein, Human, Recombinant (His)

Cat.No: TMPY-02361

Species: Human

Expression System: HEK293 Cells

TLR4 Protein, Human, Recombinant (His)

Cat.No: TMPY-02904

Species: Human

Expression System: Baculovirus Insect Cells

FGFR2 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-00972

Species: Human

Expression System: HEK293 Cells

SDF-1 Protein, Human, Recombinant

Cat.No: TMPY-02591

Species: Human

Expression System: E. coli

Prolactin Receptor Protein, Human, Recombinant (His)

Cat.No: TMPY-01053

Species: Human

Expression System: HEK293 Cells

LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06077

Species: Human

Expression System: HEK293 Cells

IL-18 Protein, Human, Recombinant

Cat.No: TMPY-00277

Species: Human

Expression System: E. coli

Complement C2 Protein, Human, Recombinant (His)

Cat.No: TMPY-00686

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Human, Recombinant (His)

Cat.No: TMPY-00381

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)

Cat.No: TMPY-04684

Species: Human

Expression System: HEK293 Cells

GFR Alpha-3/GFRA3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01458

Species: Human

Expression System: HEK293 Cells

MFGE8 Protein, Human, Recombinant (His)

Cat.No: TMPY-02836

Species: Human

Expression System: Baculovirus Insect Cells

OSMR Protein, Human, Recombinant (His)

Cat.No: TMPY-01305

Species: Human

Expression System: HEK293 Cells

CD16a Protein, Human, Recombinant (F176V, His)

Cat.No: TMPY-01964

Species: Human

Expression System: HEK293 Cells

CD131 Protein, Human, Recombinant (His)

Cat.No: TMPY-01650

Species: Human

Expression System: HEK293 Cells

CD83 Protein, Human, Recombinant (His)

Cat.No: TMPY-01829

Species: Human

Expression System: HEK293 Cells

Beta-Catenin Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-02205

Species: Human

Expression System: Baculovirus Insect Cells

Dermcidin Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00545

Species: Human

Expression System: HEK293 Cells

IGF1/IGF-I Protein, Human, Recombinant

Cat.No: TMPY-06982

Species: Human

Expression System: E. coli

TrkA Protein, Human, Recombinant (His)

Cat.No: TMPY-01084

Species: Human

Expression System: HEK293 Cells

IL-21 Protein, Human, Recombinant

Cat.No: TMPY-01963

Species: Human

Expression System: E. coli

TGF beta 3 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-06247

Species: Human

Expression System: HEK293 Cells

TREM-2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01703

Species: Mouse

Expression System: HEK293 Cells

EMAP-II/AIMP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01461

Species: Human

Expression System: E. coli

SCF Protein, Human, Recombinant (aa 1-189, His)

Cat.No: TMPY-02170

Species: Human

Expression System: Baculovirus Insect Cells

Human RSV (B1) glycoprotein G/RSV-G Protein (His)

Cat.No: TMPY-01885

Species: RSV

Expression System: HEK293 Cells

Glypican 3/GPC3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01283

Species: Human

Expression System: HEK293 Cells

BCL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-02700

Species: Human

Expression System: E. coli

IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05840

Species: Cynomolgus

Expression System: HEK293 Cells

CD299 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01032

Species: Human

Expression System: HEK293 Cells

ACRV1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01813

Species: Human

Expression System: HEK293 Cells

TEM8/ANTXR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02953

Species: Human

Expression System: HEK293 Cells

STAT6 Protein, Human, Recombinant (His)

Cat.No: TMPY-02603

Species: Human

Expression System: Baculovirus Insect Cells

ST2/IL-1 RL1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04096

Species: Mouse

Expression System: HEK293 Cells

LILRA6 Protein, Human, Recombinant (His)

Cat.No: TMPY-05781

Species: Human

Expression System: HEK293 Cells

TCN2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01003

Species: Human

Expression System: HEK293 Cells

SOST Protein, Human, Recombinant (His)

Cat.No: TMPY-00925

Species: Human

Expression System: HEK293 Cells

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